Leading Infectious Disease Research
hVIVO provides unparalleled scientific capability in respiratory infectious disease research, underpinned by decades of virology expertise and a comprehensive suite of validated Human Challenge Models across influenza, RSV, hMPV, HRV, COVID19 and other priority pathogens. Supported by BSL2 and BSL3 facilities, inhouse model development, manufacturing and integrated early phase clinical and laboratory operations, our platform enables precise characterisation of host–pathogen dynamics and high resolution evaluation of novel vaccines and therapeutics.
World leader in Human Challenge Trials
State‑of‑the‑art Human Challenge Unit
State‑of‑the‑art Human Challenge Unit facility with Containment Level 3 (BSL‑3) and onsite BSL‑3 labs.
Multiple Pathogen Capability
Over 80+ Human Challenge Studies delivered
Human Challenge Expertise
Human challenge trials provide a highly controlled and scientifically rigorous environment to evaluate the early efficacy of vaccines, antivirals, monoclonals, and immunomodulators. By exposing healthy adult participants to a well‑characterised viral or bacterial strain in a controlled setting, these studies deliver precise, early readouts that de‑risk development and accelerate decision‑making. hVIVO’s validated challenge models, integrated clinical and laboratory capabilities, and rapid data turnaround enable sponsors to reach proof‑of‑concept up to 3.5× faster than traditional outpatient trials.
Our Services
Clinical
hVIVO supports the full journey from preclinical to Phase III, transforming early Phase I data into clear direction for your product’s next steps. We enable fast success — or fast, informed failure — so you can make smarter decisions sooner.
Our integrated expertise includes:
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Rapid delivery of safety data & insights through FiH/SAD/MAD/DDI studies in our clinical pharmacology unit combined with our biometry consultancy
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Accelerate the PoC & efficacy data for your vaccine or anti-viral leveraging our globally recognised Human Challenge Trials using our world-class quarantine facility
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Expert-led design, rapid recruitment and advanced diagnostic capabilities delivered through our sites in UK and Germany to advance your Phase II/III studies
Challenge
Building on decades of unrivalled experience, hVIVO is a leading CRO with world-class expertise in delivering human challenge trials, challenge agent manufacture, a unique portfolio of infectious and respiratory disease models, and specialist drug development and clinical consultancy services.
Labs
hVIVO has a highly specialised infectious disease and immunology laboratory offering a suite of services to support pre-clinical and drug and vaccine discovery & development.
hVIVO have extended their storage offering to the biotech and pharmaceutical industries with locations in London and Cambridge, offering a dedicated GxP storage facility for biological and clinical materials in secure temperature-controlled conditions.
Consulting
hVIVO's integrated drug development consultancy supports life science innovators from early planning through clinical execution. With more than 25-years of experience, our team delivers a uniquely combined offering across CMC, non-clinical, clinical pharmacology, regulatory, data management and (translational) laboratory services, across the drug development and market authorisation spectrum.
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