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Respiratory Clinical Trials

 Respiratory Clinical Trials & Specialised Respiratory Assessments  
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Respiratory Indications

Asthma, COPD, bronchiectasis, IPF, nasal polyposis, allergic rhinitis, and atopic conditions  

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Patient Database

400,000+ active volunteer and patient database, including 80,000+ asthma patients and 26,000+ atopic participants  

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Clinical Assessments

Full suite of advanced clinical assessments for patients with respiratory conditions including spirometry, FOT, FeNO, bronchodilator responsiveness, methacholine and allergen challenges, and induced sputum 
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MAPLE-UK

Longitudinal observational study in asthma and COPD  conducted by hVIVO.  
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Owned Clinical Sites

Owned sites with PI oversight and strong KOL network including Kings College, Imperial College, and Southampton University
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Recruitment

Dedicated recruitment team continually characterising respiratory patients to minimise screen failures  

Plan Your Respiratory Trial with hVIVO

We provide end‑to‑end respiratory clinical trial execution across airway and atopic diseases with high‑quality safety, PK, and efficacy data.

Advanced Respiratory Assessments:

  • Serial Spirometry

  • Forced Oscillation Technique (FOT)

  • Fractional exhaled Nitric Oxide (FeNO)

  • Induced Sputum

  • Bronchodilator Responsiveness

  • Challenge Methodologies:

  • Methacholine Challenge

  • LPS Challenge

  • NAC/BAC Allergen Challenges

  • Human Rhinovirus Challenge

Patient Recruitment Capabilities:

  • 80,000+ asthma patients; 13,000+ by GINA

  • Ongoing characterisation programmes

  • In-house recruitment

Our Respiratory Experience Supports:

 

Start-ups: Fast access to characterised patient cohorts and scalable study support.

Biotech: Deep respiratory expertise, specialised assessments, and efficient recruitment.

Pharma: Operational capacity and validated methodologies for multi-site or propellant replacement studies

Reasons To Consider hVIVO For Your Next Respiratory Trial

  • Deep respiratory specialisation
  • Validated respiratory assessments
  • Large, precharacterised patient database
  • Trusted by global pharma sponsors
  • Leader in controlled respiratory challenge studies
  • Established community networks with KOLs

80,000+

Asthma patients

13,000+

Categorised by Gina type

26,000+

Atopic conditions

Meet Our Respiratory Team

hVIVO is led by a dynamic group of experts in their respective fields who are driving excellence throughout the organisation.

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Alex Mann

Senior Director Clinical Science

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Andrew Catchpole

Chief Scientific Officer

Melissa Bevan

Associate Medical Director

 Asthma, COPD, bronchiectasis, IPF, nasal polyposis, allergic rhinitis, atopic cohorts. 

  Recruitment is accelerated via our 400,000+ database, plus a patient registry.  
  Yes, using specialised assessments and challenge models.  
 Yes, we can support propellant replacement studies with CMC, Laboratory, consulting, regulatory, and site solutions.  

Plan your next Clinical Trial with hVIVO