Airflow obstruction (AFO) and preserved ratio impaired spirometry phenotype in asthma have been associated with more exacerbations, poorer symptoms, use of ICS, and small airway dysfunction (SAD) [Cottini et al,2025]. Here we present analysis of AFO across severities of asthma in a cross-sectional asthma cohort prior to enrolment in the MAPLE-UK longitudinal study.
Alex J Mann1, Aruna T Bansal2, Melissa Bevan1, Alex Lima1, Rachna Goburdhun1, Christine Topham1, Isaacs S1, Rees K1, Mona Bafadhel3
1 hVIVO Services Ltd, London, UK; 2 Acclarogen Ltd., UK; 3 King’s Centre for Lung Health, Kings College London, UK
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